更新日期:2023年3月15日
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姓 名
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杨显珠
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性 别
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男
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出生年月
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1984年11月
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籍贯
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安徽枞阳县
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民 族
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汉族
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政治面貌
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中国共产党党员
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最后学历
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博士研究生
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最后学位
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哲学博士
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技术职称
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教授
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导师类别
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博、硕导
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行政职务
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Email
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yangxz@scut.edu.cn
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工作单位
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医学院/生命科学研究院
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邮政编码
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通讯地址
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大学城校区B2-303
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单位电话
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个人简介
华南理工大学,生物医学科学与工程学院,教授,博士生导师、优青。主要研究领域为生物医用高分子材料、纳米药物载体等;以通讯作者发表论文60多篇,其中IF>10论文49篇,包括Nature Communications、National Science Review,Advanced Functional Materials,Nano Today,ACS Nano,Nano Letters,Advanced Science等。
工作经历
2017-至今,华南理工大学教授,博士生导师
2013-2017,合肥工业大学教授,博士生导师
2012-2012,中国科学技术大学生命科学学院,博士后
教育经历
2006-2011,中国科学技术大学,高分子化学与物理,博士学位
2002-2006,合肥工业大学,高分子化学与工程,学士学位
研究领域
实验组致力于是高分子纳米药物研究,利用功能高分子材料的设计合成,尝试解决siRNA、化疗药物、小分子抑制剂等药物体内递送难题,为癌症等重大疾病的治疗提供新策略。
发表论文
近年部分代表性成果(通讯作者以“*”标出,共第一作者“#”标出)
1. Yueqiang Zhu#, Yonghong Song#, Ziyang Cao*, Liang Dong, Song Shen, Yang Lu*, Xianzhu Yang*, A magnetically driven amoeba-like nanorobot for whole-process active drug transport, Adv. Sci., 2023, 10, 2204793.
2. Liangjie Jin#, Dongmei Yang#, Yonghong Song#, Dongdong Li* Weijia Xu Yueqiang Zhu, Cong-Fei Xu, Yang Lu*, Xianzhu Yang*, In Situ Programming of Nanovaccines for Lymph Node-targeted Delivery and Cancer Immunotherapy, ACS Nano 2022, 16, 15226−15236.
3. Liang Zhao, Dongdong Li, Yuxi Zhang, Qiaoyi Huang, Zhenghai Zhang, Chaoran Chen, Cong-Fei Xu, Xiao Chu, Yu Zhang, Xianzhu Yang*, A HSP70 Promoter-Driven CRISPR/Cas9 System Activated by ROS for Multifaceted Anticancer Immune Response and Potentiated Immunotherapy, ACS Nano, 2022, 16, 13821−13833.
4. Ziyang Cao, Dongdong Li, Liang Zhao, Mengting Liu, Pengyue Ma, Yingli Luo, Xianzhu Yang*,Bioorthogonal in situ assembly of nanomedicines as drug depots for extracellular drug delivery, Nature Communications 2022, 13, 2038.
5. Wangcheng Zhang,# Yuxi Zhang,# Yingli Luo,# Senbiao Chen, Qiaoyi Huang, Zhiting Cao, Ming Liang, Xianzhu Yang*, A Nanoconfined Loading Strategy for Highly Efficient siRNA Delivery and Cancer Therapy, Nano Today 2022, 43, 101418.
6. Yuxi Zhang,# Zhenghai Zhang,# Senlin Li, Liang Zhao, Dongdong Li, Ziyang Cao, Xiaoding Xu, and Xianzhu Yang*, A siRNA-Assisted Assembly Strategy to Simultaneously Suppress “Self” and Upregulate “Eat-Me” Signals for Nanoenabled Chemo-Immunotherapy, ACS Nano, 2021, 15, 10, 16030-16042.
7. Yueqiang Zhu,# Yonghong Song,# Ziyang Cao, Liang Dong, Yang Lu,* Xianzhu Yang,* Jun Wang,* Magnetically Actuated Active Deep Tumor Penetration of Deformable Large Nanocarriers for Enhanced Cancer Therapy, Advanced Functional Materials, 2021, 31, 2103655.
8. Junxia Wang,# Song Shen,# Jie Li, Ziyang Cao, Xianzhu Yang,* Precise Depletion of Tumor Seed and Growing Soil with Shrinkable Nanocarrier for Potentiated Cancer Chemoimmunotherapy, ACS Nano, 2021, 15, 3, 4636–4646.
9. Senbiao Chen,# Dongdong Li,# Xiaojiao Du∗, Xinyu He, Mengwen Huang, Yang Wang, Xianzhu Yang∗, Jun Wang∗ Carrier-free nanoassembly of doxorubicin prodrug and siRNA for combinationally inducing immunogenic cell death and reversing immunosuppression, Nano Today 2020, 35, 100924.
10. Yonghong Song,# Dongdong Li,# Yang Lu*, Kun Jiang, Yi Yang, Yunjun Xu, Liang Dong, Xu Yan, Daishun Ling, Xianzhu Yang*, and Shu-Hong Yu*, Ferrimagnetic mPEG-b-PHEP Copolymer Micelles Loaded with Iron Oxide Nanocubes and Emodin for Enhanced Magnetic Hyperthermia-Chemotherapy, National Science Review, 2020, 7: 723-736.