更新日期:2020年5月9日
个人简介
袁友永,教授。2007年7月于安徽大学获材料化学专业学士学位;2012年7月于中国科学技术大学获高分子化学与物理博士学位,导师为王均教授;同年8月加入新加坡国立大学进行博士后研究,导师为刘斌教授,共同指导导师为香港科技大学高分子化学家唐本忠院士;2017年7月受聘于华南理工大学回国任教,任教授、博士生导师。在国际重要学术期刊发表论文50余篇,其中第一作者论文28篇(包括Adv. Mater. 1篇、J. Am. Chem. Soc. 1篇、Angew. Chem. Int. Ed. 4篇、Adv. Funct. Mater. 1篇、Chem. Sci. 4篇、Small 2篇等),共同第一作者论文3篇(包括ACS Nano 1篇、Chem. Sci. 1篇、Biomaterials 1篇);5篇论文(曾)入围ESI高被引论文,2篇论文被作为封面报道;截至2018年6月,所有论文已被引用2250次,最高单篇他引196次,H 指数为25(以上数据来源于ISI Web of Knowledge)。此外,申请人作为主要完成人之一申请了2项PCT专利,并参与了系列丛书的2个章节的撰写。
工作经历
2017.07-至今,华南理工大学,医学院生命科学研究院,教授
2012.08-2017.07,新加坡国立大学,博士后
教育经历
2007.09-2012.07,中国科学技术大学,高分子化学与物理博士
2003.09-2007.07,安徽大学,材料化学学士
研究领域
纳米药物与药物递送系统;生物医用材料;生物成像;癌症诊疗
发表论文
1. Yansong Dong, Yalan Tu, Kewei Wang, Congfei Xu, Youyong Yuan,* Jun Wang.* A General Strategy for Macrotheranostic Prodrug Activation: Synergy by Tumor Acidic Microenvironment and Bioorthogonal Chemistry. Angew. Chem. Int. Ed., 2020, 59. 7168-7172.
2. Kewei Wang, Yalan Tu, Wang Yao, Qingyu Zong, Xuan Xiao, Rui-Meng Yang,* Xin-Qing Jiang,* Youyong Yuan.* Size-Switchable Nanoparticles with Self-Destructive and Tumor Penetration Characteristics for Site-Specific Phototherapy of Cancer. ACS Appl. Mater. Interfaces, 2020, 12, 6933-6943.
3. Yansong Dong, Bin Liu,* Youyong Yuan.* AIEgen based drug delivery systems for cancer therapy. J. Control. Release, 2018, 290, 129-137.
4. Youyong Yuan, Chengqiong Mao, Xiaojiao Du, Jinzhi Du, Feng Wang and Jun Wang*, Surface Charge Switchable Nanoparticles based on Zwitterionic Polymer for Enhanced Drug Delivery to Tumor, Adv. Mater., 2012, 24, 5476-5480.
5. Youyong Yuan, Ryan T. K. Kwok, Ben Zhong Tang* and Bin Liu*, Targeted Theranostic Platinum (IV) Prodrug with a Built-in Aggregation-Induced Emission Light-up Apoptosis Sensor for Noninvasive Early Evaluation of its Therapeutic Responses In-situ, J. Am. Chem. Soc., 2014, 136, 2546-2554.
6. Youyong Yuan, Jie Liu and Bin Liu*, Conjugated Polyelectrolyte based Polyprodrug: Targeted and Imaging Guided Photodynamic and Chemotherapy with On-demand Drug Release upon Single Light Irradiation, Angew. Chem. Int. Ed., 2014, 53, 7163-7168.
7. Youyong Yuan, Chong-Jing Zhang, Meng Gao, Ruoyu Zhang, Ben Zhong Tang and Bin Liu*, Specific Light-up Bioprobe with Aggregation-Induced Emission and Activatable Photoactivity for Targeted and Image-Guided Photodynamic Ablation of Cancer Cells, Angew. Chem. Int. Ed., 2015, 54, 1780-1786.
8. Youyong Yuan, Chong-Jing Zhang and Bin Liu*, Photoactivatable AIE Polymer for Light Controlled Gene Delivery: Concurrent Endo-/Lysosomal Escaping and DNA Unpacking, Angew. Chem. Int. Ed., 2015, 54, 11419–11423.
9. Youyong Yuan, Shidang Xu, Xiamin Cheng, Xiaolei Cai and Bin Liu*, Bioorthogonal Turn-On Probe based on AIEgen for Cancer Cell Imaging and Ablation, Angew. Chem. Int. Ed., 2016, 55, 6457-6461.
10. Youyong Yuan, Chong-Jing Zhang, Ryan T. K. Kwok, Shidang Xu, Ruoyu Zhang, Jien Wu, Ben Zhong Tang* and Bin Liu*, Light-Up Probe for Targeted and Activatable Photodynamic Therapy with Real-Time In Situ Reporting of Sensitizer Activation and Therapeutic Responses, Adv. Funct. Mater., 2015, 25, 6586–6595.